UGT2B4 anticorps (AA 111-210) (Biotin)

N° du produit ABIN705508

Cet anticorps Lapin Polyclonal détecte spécifiquement UGT2B4 dans ELISA, WB, IHC (fro) et IHC (p). Il présente une réactivité envers Humain.

Aperçu rapide pour UGT2B4 anticorps (AA 111-210) (Biotin) (ABIN705508)

Antigène: UGT2B4 (UDP Glucuronosyltransferase 2 Family, Polypeptide B4 (UGT2B4))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp UGT2B4 est conjugé à/à la Biotin

Application: ELISA, Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-UGT2B4 anticorps (Biotin)

Épitope: AA 111-210

Homologie: Human,Sheep

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human UGT2B4

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détails sur UGT2B4

Antigène: UGT2B4 (UDP Glucuronosyltransferase 2 Family, Polypeptide B4 (UGT2B4))

Autre désignation: UGT2B4

Sujet:

Synonyms: HLUG25, Hyodeoxycholic acid, UDP glucuronosyltransferase 2 family polypeptide B4, UDP glucuronosyltransferase 2B4 precursor, UDP glucuronyltransferase family 2 beta 4, UDP glycosyltransferase 2 family polypeptide B4, UDP glycosyltransferase, UDPGT, UDPGTh 1, UDPGTh1, UGT2B11, UGT2B4, UD2B4_HUMAN.

Background: The UDP-Glucuronosyltransferases (UGT) comprise a family of enzymes that detoxify and enhance the urinary excretion of a wide variety of xenobiotic and endogenous substrates by transferring glucuronic acid to sulfhydryl, hydroxyl, aromatic amino, or carboxylic acid groups. They have been subdivided into two families, UGT1 and UGT2, based on the evolutionary divergence of their genes. The enzymes of the UGT1A family play an important role in the metabolism of dietary constituents, phenols, and therapeutic drugs, and also the glucuronidation of bilirubin and iodothyronines. The enzymes of the UGT2B family are involved in the metabolism of bile acids, phenol derivatives, catecholestrogens and steroids. Although it is widely recognized that the liver is the major site of glucuronidation, it is now clear that UGT enzymes are also found in extra-hepatic tissues.

ID gène: 7363

Pathways: Steroid Hormone Biosynthesis