JAG2 anticorps (AA 201-300)

N° du produit ABIN705791

Détail du produit anti-JAG2 anticorps

Antigène: JAG2 (Jagged 2 (JAG2))

Épitope: AA 201-300

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp JAG2 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificité: There is a chance that this protein will cross-react with JAG1 based on 77 % sequence similarity

Réactivité croisée: Humain

Homologie: Mouse,Rat,Dog,Cow,Pig

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human Jagged 2

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détails sur JAG2

Antigène: JAG2 (Jagged 2 (JAG2))

Autre désignation: Jagged 2 (JAG2 Produits)

Synonymes: anticorps D12Ggc2e, anticorps Serh, anticorps mJagged2-1, anticorps sm, anticorps HJ2, anticorps SER2, anticorps jag2, anticorps serB, anticorps zgc:152855, anticorps jagged 2, anticorps jagged 2b, anticorps JAG2, anticorps jag2, anticorps Jag2, anticorps jag2b

Sujet:

Synonyms: D12Ggc2e, HJ 2, HJ2, JAG 2, JAG2, Jagged 2 precursor, Jagged2, Syndactylism.

Background: Jagged 2 is a Notch ligand involved in the mediation of Notch signaling. Jagged 2 is expressed in heart, placenta and skeletal muscle and to a lesser extend in pancreas. Very low expression in brain, lung, liver and kidney. The Notch signaling pathway is an intercellular signaling mechanism that is essential for proper embryonic development. Members of the Notch gene family encode transmembrane receptors that are critical for various cell fate decisions. Jagged 2 is one of several ligands that activate Notch and related receptors. Two transcript variants encoding different isoforms have been found for Jagged 2.

ID gène: 3714

UniProt: Q9Y219

Pathways: Signalisation Notch, Sensory Perception of Sound