XRN1 anticorps (AA 1455-1706)

N° du produit ABIN7090717

L’anticorps Souris Monoclonal anti-XRN1 a été validé pour WB. Il convient pour détecter XRN1 dans des échantillons de Humain.

Aperçu rapide pour XRN1 anticorps (AA 1455-1706) (ABIN7090717)

Antigène: XRN1 (5'-3' Exoribonuclease 1 (XRN1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp XRN1 est non-conjugé

Application: Western Blotting (WB)

Clone: F12D4

Détail du produit anti-XRN1 anticorps

Épitope: AA 1455-1706

Réactivité croisée: Humain

Homologie: Mouse

Purification: Purified by Protein G.

Immunogène: Recombinant human XRN1 between1455-1706 amino acids.

Isotype: IgG1

Information d'application

Indications d'application: WB 1:300-5000

Restrictions: For Research Use only

Stockage

Concentration: 0.5 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détails sur XRN1

Antigène: XRN1 (5'-3' Exoribonuclease 1 (XRN1))

Autre désignation: XRN1

Sujet:

Synonyms: XRN1_HUMAN, Dhm2, mXRN1, SEP1, Strand-exchange protein 1 homolog, 5'-3' exoribonuclease 1.

Background: Lamins are type V intermediate filament proteins and are grouped into constitutively expressed B-type lamins and developmentally regulated A-type lamins. Lamin-binding proteins in the nuclear lamina and the nuclear interior include several protein families and/or types of proteins in higher eukaryotes such as the inner nuclear membrane proteins, lamin B receptor, emerin, MANI, three isoforms of lamina-associated polypeptide 1 (LAP 1), and several isoforms of LAP 2. Up to six LAP 2 isoforms derive from a single gene by alternative splicing in mammals and various isoforms have been described in Xenopus. The best characterized LAP2 isoforms are the inner nuclear membrane protein LAP 2 beta and the nucleoplasmic protein LAP 2 alpha, which are identical in their N-terminal 187-amino acid constant region but differ in their C termini. LAP 2 alpha specifically interacts with A-type lamins within the nuclear interior as part of a detergent- and salt-resistant nucleoskeletal structure.

ID gène: 54464

UniProt: Q8IZH2