CDKN2B anticorps

N° du produit ABIN706166

L’anticorps Lapin Polyclonal anti-CDKN2B a été validé pour WB, IHC (p) et IF (p). Il convient pour détecter CDKN2B dans des échantillons de Humain, Souris, Rat, Chien, Boeuf (Vache) et Poulet.

Aperçu rapide pour CDKN2B anticorps (ABIN706166)

Antigène: CDKN2B (Cyclin-Dependent Kinase Inhibitor 2B (p15, Inhibits CDK4) (CDKN2B))

Reactivité: Humain, Souris, Rat, Chien, Boeuf (Vache), Poulet

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CDKN2B est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Détail du produit anti-CDKN2B anticorps

Réactivité croisée: Rat (Rattus), Poulet, Chien, Boeuf (Vache)

Purification: purified by Protein A and peptide affinity chromatography

Immunogène: KLH conjugated synthetic peptide derived from human CDKN2B

Isotype: IgG

Information d'application

Indications d'application: WB(1:100-500)
Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 µg/µL

Buffer: Aqueous buffered solution containing 100 µg/mL BSA, 50 % glycerol and 0.09 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C for 12 months

Date de péremption: 12 months

Détails sur CDKN2B

Antigène: CDKN2B (Cyclin-Dependent Kinase Inhibitor 2B (p15, Inhibits CDK4) (CDKN2B))

Autre désignation: CDKN2B

Sujet: P15 INK4b / MTS 2 (Mitotic Inhibitor / Suppressor Protein) is a specific inhibitor of cdk 4 / cdk 6 and is periodically expressed during the cell cycle. Reportedly, p15 INK4b expression is induced approximately 30 fold in human keratinocytes by treatment with TGF beta, suggesting that p15 INK4b may act as an effector of TGF beta mediated cell cycle arrest. p15 INK4b is mapped to chromosome 9p21, a region of frequent loss in a wide variety of cancers.

Poids moléculaire: 15kDa

ID gène: 1030

Pathways: Cycle Cellulaire, Mitotic G1-G1/S Phases