ANKRD15 anticorps

N° du produit ABIN7090750

L’anticorps Souris Monoclonal anti-ANKRD15 a été validé pour WB et IHC (p). Il convient pour détecter ANKRD15 dans des échantillons de Humain.

Aperçu rapide pour ANKRD15 anticorps (ABIN7090750)

Antigène: ANKRD15 (Ankyrin Repeat Domain 15 (ANKRD15))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp ANKRD15 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: Y6S1

Détail du produit anti-ANKRD15 anticorps

Homologie: Human

Immunogène: Recombinant human KANK1.

Information d'application

Indications d'application: WB 1:300-5000
IHC-P 1:200-400

Restrictions: For Research Use only

Stockage

Concentration: 0.5 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détails sur ANKRD15

Antigène: ANKRD15 (Ankyrin Repeat Domain 15 (ANKRD15))

Autre désignation: KANK1

Sujet:

Synonyms: ANKRD 15, Ankyrin repeat domain 15, Ankyrin repeat domain containing protein 15, Ankyrin repeat domain-containing protein 15, DKFZp451G231, KANK, KANK1_HUMAN, KIAA0172, Kidney ankyrin repeat containing protein, Kidney ankyrin repeat-containing protein, KN motif and ankyrin repeat domain-containing protein 1, MGC43128.

Background: Involved in the control of cytoskeleton formation by regulating actin polymerization. Inhibits actin fiber formation and cell migration. Inhibits RhoA activity, the function involves phosphorylation through PI3K/Akt signaling and may depend on the competetive interaction with 14-3-3 adapter proteins to sequester them from active complexes. Inhibits the formation of lamellipodia but not of filopodia, the function may depend on the competetive interaction with BAIAP2 to block its association with activated RAC1. Inhibits fibronectin-mediated cell spreading, the function is partially mediated by BAIAP2. Inhibits neurite outgrowth. Involved in the establishment and persistence of cell polarity during directed cell movement in wound healing. In the nucleus, is involved in beta-catenin-dependent activation of transcription. Potential tumor suppressor for renal cell carcinoma.

ID gène: 23189

UniProt: Q14678

Pathways: Regulation of Actin Filament Polymerization