CDKN2B anticorps (HRP)

N° du produit ABIN706175

L’anticorps anti-CDKN2B Polyclonal Lapin est utilisé pour la détection de CDKN2B dans des échantillons de Humain. Il a été validé pour WB et IHC (p).

Aperçu rapide pour CDKN2B anticorps (HRP) (ABIN706175)

Antigène: CDKN2B (Cyclin-Dependent Kinase Inhibitor 2B (p15, Inhibits CDK4) (CDKN2B))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CDKN2B est conjugé à/à la HRP

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-CDKN2B anticorps (HRP)

Fonction: CDKN2B/p15 INK4b Polyclonal Antibody, HRP Conjugated

Réactivité croisée: Poulet, Boeuf (Vache), Chien, Humain, Souris, Rat

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human CDKN2B

Isotype: IgG

Information d'application

Indications d'application: WB(1:300-5000), IHC-P(1:200-400)

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur CDKN2B

Antigène: CDKN2B (Cyclin-Dependent Kinase Inhibitor 2B (p15, Inhibits CDK4) (CDKN2B))

Autre désignation: CDKN2B

Sujet:

Synonyms: CDK inhibitory protein, CDK4B Inhibitor, CDKN2B, Cyclin dependent kinase 4 inhibitor B, Cyclin Dependent Kinase Inhibitor 2B, Cyclin dependent kinase inhibitor 2B p15 inhibits CDK4, Cyclin-dependent kinases 4 and 6 binding protein, INK4B, MTS 2, MTS2, Multiple Tumor Supressor 2, p14 CDK inhibitor, p14 INK4b, P15, p15 CDK inhibitor, p15 inhibits CDK4, p15 INK4b, P15INK4B, p15INK4B, TP 15, TP15.

Background: p15 INK4b / MTS 2 (Mitotic Inhibitor / Suppressor Protein) is a specific inhibitor of cdk 4 / cdk 6 and is periodically expressed during the cell cycle. Reportedly, p15 INK4b expression is induced approximately 30 fold in human keratinocytes by treatment with TGF beta, suggesting that p15 INK4b may act as an effector of TGF beta mediated cell cycle arrest. p15 INK4b is mapped to chromosome 9p21, a region of frequent loss in a wide variety of cancers.

Poids moléculaire: 15kDa

ID gène: 1030

UniProt: P42772

Pathways: Cycle Cellulaire, Mitotic G1-G1/S Phases