EPH Receptor B4 anticorps

N° du produit ABIN7091064

Cet anticorps Souris Monoclonal détecte spécifiquement EPH Receptor B4 dans WB. Il présente une réactivité envers Humain.

Aperçu rapide pour EPH Receptor B4 anticorps (ABIN7091064)

Antigène: EPH Receptor B4 (EPHB4)

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp EPH Receptor B4 est non-conjugé

Application: Western Blotting (WB)

Clone: B12M1

Détail du produit anti-EPH Receptor B4 anticorps

Homologie: Human

Immunogène: Recombinant human EPHB4.

Information d'application

Indications d'application: WB 1:300-5000

Restrictions: For Research Use only

Stockage

Concentration: 0.5 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détails sur EPH Receptor B4

Antigène: EPH Receptor B4 (EPHB4)

Autre désignation: EPHB4

Sujet:

Synonyms: Eph receptor B4, EPHB4_HUMAN, Ephrin type-B receptor 4, Hepatoma Transmembrane Kinase, HTK, MYK1, TYRO11, Tyrosine-protein kinase receptor HTK, Tyrosine-protein kinase TYRO11.

Background: Receptor tyrosine kinase which binds promiscuously transmembrane ephrin-B family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Together with its cognate ligand/functional ligand EFNB2 plays a central role in heart morphogenesis and angiogenesis through regulation of cell adhesion and cell migration. EPHB4-mediated forward signaling controls cellular repulsion and segregation form EFNB2-expressing cells. Plays also a role in postnatal blood vessel remodeling, morphogenesis and permeability and is thus important in the context of tumor angiogenesis.

ID gène: 2050

UniProt: P54760

Pathways: Signalisation RTK