MBP anticorps (AA 241-304)

N° du produit ABIN7091371

L’anticorps anti-MBP Polyclonal Lapin est utilisé pour la détection de MBP dans des échantillons de Humain. Il a été validé pour WB, IF, IHC (p) et IHC (fro).

Aperçu rapide pour MBP anticorps (AA 241-304) (ABIN7091371)

Antigène: MBP

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MBP est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Détail du produit anti-MBP anticorps

Épitope: AA 241-304

Fonction: MBP polyclonal Antibody

Réactivité croisée: Humain, Souris, Rat

Homologie: Dog,Cow,Sheep,Pig,Horse,Rabbit

Purification: affinity Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human MBP

Isotype: IgG

Information d'application

Indications d'application: WB(WB=1:500-2000), IHC-P(1:500-2000), IHC-F(1:500-2000), IF(1:500-2000)

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détails sur MBP

Antigène: MBP

Sujet:

Synonyms: Myelin Basic Protein, Myelin basic protien, GDB, Golli MBP, Hemopoietic MBP, HMBPR, HUGO, MBP, MGC99675, MLD, Myelin A1 Protein, Myelin Deficient, Myelin Membrane Encephalitogenic Protein, SHI, Shiverer, SP, MBP_HUMAN .

Background: The classic group of MBP isoforms (isoform 4-isoform 14) are with PLP the most abundant protein components of the myelin membrane in the CNS. They have a role in both its formation and stabilization. The smaller isoforms might have an important role in remyelination of denuded axons in multiple sclerosis. The non-classic group of MBP isoforms (isoform 1-isoform 3/Golli-MBPs) may preferentially have a role in the early developing brain long before myelination, maybe as components of transcriptional complexes, and may also be involved in signaling pathways in T-cells and neural cells. Differential splicing events combined with optional post-translational modifications give a wide spectrum of isomers, with each of them potentially having a specialized function. Induces T-cell proliferation.

ID gène: 4155

UniProt: P02686