MAGED1 anticorps (AA 50-200)

N° du produit ABIN7091377

L’anticorps Souris Monoclonal anti-MAGED1 a été validé pour WB. Il convient pour détecter MAGED1 dans des échantillons de Humain.

Aperçu rapide pour MAGED1 anticorps (AA 50-200) (ABIN7091377)

Antigène: MAGED1 (Melanoma Antigen Family D, 1 (MAGED1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp MAGED1 est non-conjugé

Application: Western Blotting (WB)

Clone: C5D3

Détail du produit anti-MAGED1 anticorps

Épitope: AA 50-200

Homologie: Human

Immunogène: KLH conjugated synthetic peptide derived from human MAGED1

Information d'application

Indications d'application: WB 1:300-5000

Restrictions: For Research Use only

Stockage

Concentration: 0.5 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détails sur MAGED1

Antigène: MAGED1 (Melanoma Antigen Family D, 1 (MAGED1))

Autre désignation: MAGED1

Sujet:

Synonyms: DLXIN 1, MAGD1_HUMAN, MAGE D1 antigen, MAGE tumor antigen CCF, MAGE-D1 antigen, Melanoma antigen family D 1, Melanoma associated antigen D1, Melanoma-associated antigen D1, Neurotrophin receptor interacting MAGE homolog, Neurotrophin receptor-interacting MAGE homolog, NRAGE, PP2250.

Background: Involved in the apoptotic response after nerve growthfactor (NGF) binding in neuronal cells. Binds NGFR/p75NTR andantagonizes its association with NTRK1/TrkA, inhibits cell cycleprogression, and facilitates NGFR-mediated apoptosis. May act as aregulator of the function of DLX family members. May regulateTP53/p53 transcriptional activity and inhibit cell proliferation.Enhances TP53 phosphorylation and accumulation. May enhanceubiquitin ligase activity of RING-type zinc finger-containing E3ubiquitin-protein ligases. Proposed to act through recruitmentand/or stabilization of the Ubl-conjugating enzyme (E2) at theE3:substrate complex.

ID gène: 9500

UniProt: Q9Y5V3

Pathways: Neurotrophin Signaling Pathway