MAGED1 anticorps (AA 50-200)
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- Antigène Voir toutes MAGED1 Anticorps
- MAGED1 (Melanoma Antigen Family D, 1 (MAGED1))
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Épitope
- AA 50-200
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Reactivité
- Humain
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp MAGED1 est non-conjugé
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Application
- Western Blotting (WB)
- Homologie
- Human
- Immunogène
- KLH conjugated synthetic peptide derived from human MAGED1
- Clone
- C5D3
- Top Product
- Discover our top product MAGED1 Anticorps primaire
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- Indications d'application
- WB 1:300-5000
- Restrictions
- For Research Use only
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- Concentration
- 0.5 μg/μL
- Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C,-20 °C
- Stockage commentaire
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- Date de péremption
- 12 months
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- Antigène
- MAGED1 (Melanoma Antigen Family D, 1 (MAGED1))
- Autre désignation
- MAGED1 (MAGED1 Produits)
- Synonymes
- anticorps MAGED1, anticorps DLXIN-1, anticorps NRAGE, anticorps 2810433C11Rik, anticorps 5430405L04Rik, anticorps DXBwg1492e, anticorps Dlixin, anticorps Dlxin-1, anticorps Dlxin1, anticorps MAGE-D1, anticorps mFLJ00163, anticorps Nrage, anticorps MAGE family member D1, anticorps melanoma antigen family D, 1, anticorps melanoma antigen, family D, 1, anticorps MAGED1, anticorps Maged1
- Sujet
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Synonyms: DLXIN 1, MAGD1_HUMAN, MAGE D1 antigen, MAGE tumor antigen CCF, MAGE-D1 antigen, Melanoma antigen family D 1, Melanoma associated antigen D1, Melanoma-associated antigen D1, Neurotrophin receptor interacting MAGE homolog, Neurotrophin receptor-interacting MAGE homolog, NRAGE, PP2250.
Background: Involved in the apoptotic response after nerve growthfactor (NGF) binding in neuronal cells. Binds NGFR/p75NTR andantagonizes its association with NTRK1/TrkA, inhibits cell cycleprogression, and facilitates NGFR-mediated apoptosis. May act as aregulator of the function of DLX family members. May regulateTP53/p53 transcriptional activity and inhibit cell proliferation.Enhances TP53 phosphorylation and accumulation. May enhanceubiquitin ligase activity of RING-type zinc finger-containing E3ubiquitin-protein ligases. Proposed to act through recruitmentand/or stabilization of the Ubl-conjugating enzyme (E2) at theE3:substrate complex.
- ID gène
- 9500
- UniProt
- Q9Y5V3
- Pathways
- Neurotrophin Signaling Pathway
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