R-Spondin 3 anticorps (AA 22-100)
Aperçu rapide pour R-Spondin 3 anticorps (AA 22-100) (ABIN7091621)
Antigène
Voir toutes R-Spondin 3 (RSPO3) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 22-100
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Réactivité croisée
- Humain
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Homologie
- Mouse,Rat,Dog,Cow,Pig,Horse,Cat,Rabbit,Guinea Pig
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Purification
- Purified by Protein A.
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Immunogène
- KLH conjugated synthetic peptide derived from human RSPO3
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Isotype
- IgG
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Indications d'application
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WB 1:300-5000
ELISA 1:500-1000 -
Restrictions
- For Research Use only
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Concentration
- 1 μg/μL
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Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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Agent conservateur
- ProClin
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Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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Date de péremption
- 12 months
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- R-Spondin 3 (RSPO3)
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Autre désignation
- RSPO3
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Sujet
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Synonyms: CRISTIN1, hPWTSR, hRspo3, Protein with TSP type-1 repeat, PWTSR, R-spondin 3 homolog, R-spondin-3 [Precursor], R-spondin-3, Roof plate specific spondin-3, Roof plate-specific spondin-3, RSPO3_HUMAN, Thrombospondin type I domain containing 2, Thrombospondin type-1 domain-containing protein 2, THSD2.
Background: Activator of the beta-catenin signaling cascade, leading to TCF-dependent gene activation. Acts both in the canonical Wnt/beta-catenin-dependent pathway, possibly via a direct interaction with Wnt proteins, and in a Wnt-independent beta catenin pathway through a receptor signaling pathway that may not use frizzled/LRP receptors. Acts as a ligand for frizzled FZD8 and LRP6. May negatively regulate the TGF-beta pathway.
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ID gène
- 84870
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UniProt
- Q9BXY4
Antigène
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