R-Spondin 3 anticorps (AA 22-100) (HRP)

N° du produit ABIN7091622

Cet anticorps Lapin Polyclonal détecte spécifiquement R-Spondin 3 dans WB et ELISA. Il présente une réactivité envers Humain.

Aperçu rapide pour R-Spondin 3 anticorps (AA 22-100) (HRP) (ABIN7091622)

Antigène: R-Spondin 3 (RSPO3)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp R-Spondin 3 est conjugé à/à la HRP

Application: Western Blotting (WB), ELISA

Détail du produit anti-R-Spondin 3 anticorps (HRP)

Épitope: AA 22-100

Réactivité croisée: Humain

Homologie: Mouse,Rat,Dog,Cow,Pig,Horse,Cat,Rabbit,Guinea Pig

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human RSPO3

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000

Restrictions: For Research Use only

Stockage

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Détails sur R-Spondin 3

Antigène: R-Spondin 3 (RSPO3)

Autre désignation: RSPO3

Sujet:

Synonyms: CRISTIN1, hPWTSR, hRspo3, Protein with TSP type-1 repeat, PWTSR, R-spondin 3 homolog, R-spondin-3 [Precursor], R-spondin-3, Roof plate specific spondin-3, Roof plate-specific spondin-3, RSPO3_HUMAN, Thrombospondin type I domain containing 2, Thrombospondin type-1 domain-containing protein 2, THSD2.

Background: Activator of the beta-catenin signaling cascade, leading to TCF-dependent gene activation. Acts both in the canonical Wnt/beta-catenin-dependent pathway, possibly via a direct interaction with Wnt proteins, and in a Wnt-independent beta catenin pathway through a receptor signaling pathway that may not use frizzled/LRP receptors. Acts as a ligand for frizzled FZD8 and LRP6. May negatively regulate the TGF-beta pathway.

ID gène: 84870

UniProt: Q9BXY4