RIPK3 anticorps

N° du produit ABIN7091641

L’anticorps anti-RIPK3 Monoclonal produit chez le Souris a été validé pour WB. Il convient pour la détection de RIPK3 dans des échantillons provenant de Humain. }

Aperçu rapide pour RIPK3 anticorps (ABIN7091641)

Antigène: RIPK3 (Receptor-Interacting serine-threonine Kinase 3 (RIPK3))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp RIPK3 est non-conjugé

Application: Western Blotting (WB)

Clone: D11F6

Détail du produit anti-RIPK3 anticorps

Homologie: Human

Immunogène: Recombinant human RIPK3.

Information d'application

Indications d'application: WB 1:300-5000

Restrictions: For Research Use only

Stockage

Concentration: 0.5 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détails sur RIPK3

Antigène: RIPK3 (Receptor-Interacting serine-threonine Kinase 3 (RIPK3))

Autre désignation: RIPK3

Sujet:

Synonyms: Receptor interacting protein 3, Receptor interacting serine threonine kinase 3, Receptor interacting serine/threonine protein kinase 3, Receptor-interacting protein 3, Receptor-interacting serine/threonine-protein kinase 3, RIP 3, RIP like protein kinase 3, RIP-3, RIP-like protein kinase 3, RIPK 3, RIPK3_HUMAN.

Background: Essential for programmed necrosis in response to death-inducing TNF-alpha family members. Upon induction of necrosis, RIPK3 interacts with, and phosphorylates RIPK1 to form a necrosis-inducing complex. RIPK3 binds to and enhances the activity of three metabolic enzymes: GLUL, GLUD1, and PYGL. These metabolic enzymes may eventually stimulate the tricarboxylic acid cycle and oxidative phosphorylation, which could result in enhanced ROS production.

ID gène: 11035

UniProt: Q9Y572

Pathways: Activation of Innate immune Response, Toll-Like Receptors Cascades