RCC1 anticorps

N° du produit ABIN7091643

Cet anticorps Souris Monoclonal détecte spécifiquement RCC1 dans WB. Il présente une réactivité envers Humain.

Aperçu rapide pour RCC1 anticorps (ABIN7091643)

Antigène: RCC1 (Regulator of Chromosome Condensation 1 (RCC1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp RCC1 est non-conjugé

Application: Western Blotting (WB)

Clone: G14A2

Détail du produit anti-RCC1 anticorps

Homologie: Human,Mouse

Immunogène: Recombinant human RCC1.

Isotype: IgG1

Information d'application

Indications d'application: WB 1:300-5000

Restrictions: For Research Use only

Stockage

Concentration: 0.5 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détails sur RCC1

Antigène: RCC1 (Regulator of Chromosome Condensation 1 (RCC1))

Autre désignation: RCC1

Sujet:

Synonyms: Cell cycle regulatory protein, CHC 1, CHC1, Chromosome condensation 1, Chromosome condensation protein 1, Guanine nucleotide releasing protein, HERC2, Ran GEF, RanGEF, RCC 1, RCC1 I, Regulator of chromosome condensation 1, Regulator of chromosome condensation, SHEP1, RCC1_HUMAN.

Background: Guanine-nucleotide releasing factor that promotes the exchange of Ran-bound GDP by GTP. Involved in the regulation of onset of chromosome condensation in the S phase. Binds both to the nucleosomes and double-stranded DNA. RCC1-Ran complex (together with other proteins) acts as a component of a signal transmission pathway that detects unreplicated DNA. Plays a key role in nucleo-cytoplasmic transport, mitosis and nuclear-envelope assembly.

ID gène: 1104

UniProt: P18754

Pathways: Chromatin Binding, Protein targeting to Nucleus