TBP anticorps (Biotin)

N° du produit ABIN7091716

Détail du produit anti-TBP anticorps (Biotin)

Antigène: TBP (TATA Box Binding Protein (TBP))

Reactivité: Humain, Souris, Rat

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp TBP est conjugé à/à la Biotin

Application: Western Blotting (WB)

Réactivité croisée: Humain, Souris, Rat

Purification: Purified by Protein G.

Immunogène: Recombinant human TBP protein

Clone: 6G8

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000

Restrictions: For Research Use only

Stockage

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détails sur TBP

Antigène: TBP (TATA Box Binding Protein (TBP))

Autre désignation: TATA binding protein TBP/TBP (TBP Produits)

Synonymes: anticorps GTF2D, anticorps GTF2D1, anticorps HDL4, anticorps SCA17, anticorps TFIID, anticorps Gtf2d, anticorps fd20h06, anticorps si:zc101n13.2, anticorps wu:fd20h06, anticorps zgc:66213, anticorps TBP1, anticorps TBP, anticorps tbp, anticorps CG9874, anticorps Dmel\\CG9874, anticorps RBP, anticorps TBP38, anticorps TFIIDtau, anticorps TfIID, anticorps dTBP, anticorps dTFIID, anticorps dTbp, anticorps dtbp, anticorps gtf2d, anticorps gtf2d1, anticorps sca17, anticorps tfiid, anticorps tfiidtau, anticorps xtbp, anticorps tbp-a, anticorps tbp-b, anticorps TATA-box binding protein, anticorps TATA box binding protein, anticorps TATA binding protein, anticorps TATA-box binding protein L homeolog, anticorps TATA-box-binding protein, anticorps TATA-box binding protein S homeolog, anticorps TBP, anticorps Tbp, anticorps tbp, anticorps tbp.L, anticorps tbp.S

Sujet:

Synonyms: GTF2D, TFIID, GTF2D1, MGC117320, MGC126054, MGC126055, SCA 17, SCA17, TATA binding factor, TATA box binding protein, TATA box factor, TATA sequence binding protein, TATA sequence-binding protein, TATA binding protein TBP, TATA-binding factor, TATA-box factor, TATA-box-binding protein, TBP, TBP_HUMAN, TF2D, TFIID, Transcription initiation factor TFIID TBP subunit.

Background: Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. This gene encodes TBP, the TATA-binding protein. A distinctive feature of TBP is a long string of glutamines in the N-terminus. This region of the protein modulates the DNA binding activity of the C terminus, and modulation of DNA binding affects the rate of transcription complex formation and initiation of transcription. The number of CAG repeats encoding the polyglutamine tract is usually 32-39, and expansion of the number of repeats increases the length of the polyglutamine string and is associated with spinocerebellar ataxia 17, a neurodegenerative disorder classified as a polyglutamine disease. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2010]

ID gène: 6908

UniProt: P20226

Pathways: Signalisation WNT