TSC1 anticorps

N° du produit ABIN7091774

Cet anticorps anti-TSC1 est un anticorps Souris Monoclonal détectant TSC1 dans WB. Adapté pour Humain.

Aperçu rapide pour TSC1 anticorps (ABIN7091774)

Antigène: TSC1 (Tuberous Sclerosis 1 (TSC1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp TSC1 est non-conjugé

Application: Western Blotting (WB)

Clone: K6F13

Détail du produit anti-TSC1 anticorps

Homologie: Human

Immunogène: Recombinant human TSC1 (Fragment) (His-tagged).

Isotype: IgG2b

Information d'application

Indications d'application: WB 1:300-5000

Restrictions: For Research Use only

Stockage

Concentration: 0.5 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détails sur TSC1

Antigène: TSC1 (Tuberous Sclerosis 1 (TSC1))

Autre désignation: TSC1

Sujet:

Synonyms: LAM, Hamartin, Tuberous sclerosis 1 protein, TSC1_HUMAN, KIAA0243, TSC, Tuberous sclerosis 1.

Background: In complex with TSC2, inhibits the nutrient-mediated or growth factor-stimulated phosphorylation of S6K1 and EIF4EBP1 by negatively regulating mTORC1 signaling. Seems not to be required for TSC2 GAP activity towards RHEB. Implicated as a tumor suppressor. Involved in microtubule-mediated protein transport, but this seems to be due to unregulated mTOR signaling.

ID gène: 7248

UniProt: Q92574

Pathways: Signalisation RTK, AMPK Signaling, Regulation of Cell Size, Tube Formation