CSF1R anticorps (AA 20-514)

N° du produit ABIN7092907

L’anticorps anti-CSF1R Monoclonal Lapin est utilisé pour la détection de CSF1R dans des échantillons de Humain. Il a été validé pour ELISA et FACS.

Aperçu rapide pour CSF1R anticorps (AA 20-514) (ABIN7092907)

Antigène: CSF1R (Colony Stimulating Factor 1 Receptor (CSF1R))

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp CSF1R est non-conjugé

Application: ELISA, Flow Cytometry (FACS)

Clone: DM106

Détail du produit anti-CSF1R anticorps

Épitope: AA 20-514

Fonction: Anti-CSF1R antibody(DM106), Rabbit mAb

Purification: Purified from cell culture supernatant by affinity chromatography

Immunogène: Recombinant human CSF1R (Ile20-Leu514) (ABIN6961125) produced by using human HEK293 cells

Isotype: IgG

Information d'application

Indications d'application: ELISA 1:5000-10000, Flow Cyt 1:100

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Please see Certificate of Analysis for specific instructions of reconstitution.

Buffer: Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

Stock: -20 °C,-80 °C

Stockage commentaire: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Date de péremption: 12 months

Détails sur CSF1R

Antigène: CSF1R (Colony Stimulating Factor 1 Receptor (CSF1R))

Autre désignation: CSF1R

Sujet: Synonyms:CSF1R,C-FMS,CD115,CSFR,FIM2,FMS,M-CSFR
Description:The protein encoded by this gene is the receptor for colony stimulating factor 1, a cytokine which controls the production, differentiation, and function of macrophages. This receptor mediates most if not all of the biological effects of this cytokine. Ligand binding activates the receptor kinase through a process of oligomerization and transphosphorylation. The encoded protein is a tyrosine kinase transmembrane receptor and member of the CSF1/PDGF receptor family of tyrosine-protein kinases. Mutations in this gene have been associated with a predisposition to myeloid malignancy. The first intron of this gene contains a transcriptionally inactive ribosomal protein L7 processed pseudogene oriented in the opposite direction. Alternative splicing results in multiple transcript variants. Expression of a splice variant from an LTR promoter has been found in Hodgkin lymphoma (HL), HL cell lines and anaplastic large cell lymphoma.

Poids moléculaire: 55.6 kDa

ID gène: 1436

UniProt: P07333

Pathways: Signalisation RTK, Inositol Metabolic Process, Cell-Cell Junction Organization