MME anticorps (AA 52-750)

N° du produit ABIN7092975

Cet anticorps Lapin Monoclonal détecte spécifiquement MME dans FACS et ELISA. Il présente une réactivité envers Humain.

Aperçu rapide pour MME anticorps (AA 52-750) (ABIN7092975)

Antigène: MME (Membrane Metallo-Endopeptidase (MME))

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp MME est non-conjugé

Application: Flow Cytometry (FACS), ELISA

Clone: DM176

Détail du produit anti-MME anticorps

Épitope: AA 52-750

Purification: Powder

Immunogène: Recombinant human CD10(Tyr52-Trp750) (ABIN6964096) produced by using human HEK293 cells

Isotype: IgG

Information d'application

Indications d'application: ELISA 1/5000-10000,Flow Cyt 1/100

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Reconstitute with deionized water

Buffer: Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.,0.1 % Procline 300

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Date de péremption: 12 months

Détails sur MME

Antigène: MME (Membrane Metallo-Endopeptidase (MME))

Autre désignation: CD10

Sujet: Synonyms:MME,CALLA,CD10,DKFZp686O16152,MGC126681,MGC126707,NEP,SFE,Neprilysin
Description:The protein encoded by this gene is a type II transmembrane glycoprotein and a common acute lymphocytic leukemia antigen that is an important cell surface marker in the diagnosis of human acute lymphocytic leukemia (ALL). The encoded protein is present on leukemic cells of pre-B phenotype, which represent 85 % of cases of ALL. This protein is not restricted to leukemic cells, however, and is found on a variety of normal tissues. The protein is a neutral endopeptidase that cleaves peptides at the amino side of hydrophobic residues and inactivates several peptide hormones including glucagon, enkephalins, substance P, neurotensin, oxytocin, and bradykinin.

Poids moléculaire: 85.5KDa

Pathways: Signalisation RTK, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Smooth Muscle Cell Migration