CTLA4 anticorps (AA 36-161) (Biotin)

N° du produit ABIN7092999

Cet anticorps Lapin Monoclonal détecte spécifiquement CTLA4 dans FACS et ELISA. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour CTLA4 anticorps (AA 36-161) (Biotin) (ABIN7092999)

Antigène: CTLA4 (Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4))

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp CTLA4 est conjugé à/à la Biotin

Application: Flow Cytometry (FACS), ELISA

Clone: DM50

Détail du produit anti-CTLA4 anticorps (Biotin)

Épitope: AA 36-161

Fonction: Biotinylated Anti-CTLA4 antibody(DM50), Rabbit mAb

Purification: Purified from cell culture supernatant by affinity chromatography

Immunogène: Recombinant human  CTLA4(Gln36-Ser161) (ABIN6961090) produced by using human HEK293 cells

Isotype: IgG

Information d'application

Indications d'application: ELISA 1:5000-10000, Flow Cyt 1:100

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Please see Certificate of Analysis for specific instructions of reconstitution.

Buffer: Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

Stock: -20 °C,-80 °C

Stockage commentaire: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Date de péremption: 12 months

Détails sur CTLA4

Antigène: CTLA4 (Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4))

Autre désignation: CTLA-4

Sujet: Synonyms:CTLA4, CD152
Description:Leukocyte surface antigen CD47 is also known as Antigenic surface determinant protein OA3, Integrin-associated protein (IAP) and Protein MER6. CD47 contains 1 Ig-like V-type (immunoglobulin-like) domain. CD47 is very broadly distributed on normal adult tissues. CD47 has a role in both cell adhesion by acting as an adhesion receptor for THBS1 on platelets, and in the modulation of integrins and plays an important role in memory formation and synaptic plasticity in the hippocampus by similarity. CD47 is the receptor for SIRPA, binding to which prevents maturation of immature dendritic cells and inhibits cytokine production by mature dendritic cells. CD47 Interaction with SIRPG mediates cell-cell adhesion, enhances superantigen-dependent T-cell-mediated proliferation and costimulates T-cell activation.

Poids moléculaire: 24.6 kDa

ID gène: 1493

UniProt: P16410

Pathways: Cancer Immune Checkpoints