XRN1 anticorps (AA 200-450)
Aperçu rapide pour XRN1 anticorps (AA 200-450) (ABIN7111134)
Antigène
Voir toutes XRN1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 200-450
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Fonction
- XRN1 antibody
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Purification
- Immunogen affinity purified
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Pureté
- ≥95 % as determined by SDS-PAGE
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Immunogène
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Immunogen sequence: 200-450aa
Immunogen: 5'-3' exoribonuclease 1
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Isotype
- IgG
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Indications d'application
- WB: 1:200-1:2000, IHC: 1:20-1:200, IF: 1:20-1:200
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freeze / thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- -20°C for 12 months
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Date de péremption
- 12 months
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- XRN1 (5'-3' Exoribonuclease 1 (XRN1))
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Autre désignation
- XRN1
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Sujet
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Synonyms: 5'-3' exoribonuclease 1|Strand-exchange protein 1 homolog|XRN1|45536
Background: Major 5'-3' exoribonuclease involved in mRNA decay. Required for the 5'-3'-processing of the G4 tetraplex-containing DNA and RNA substrates. The kinetic of hydrolysis is faster for G4 RNA tetraplex than for G4 DNA tetraplex and monomeric RNA tetraplex. Binds to RNA and DNA(By similarity). Plays a role in replication-dependent histone mRNA degradation. May act as a tumor suppressor protein in osteogenic sarcoma(OGS).
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Poids moléculaire
- 192 kDa
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ID gène
- 54464
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UniProt
- Q8IZH2
Antigène
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