AKR1C4 anticorps

N° du produit ABIN7111464

Cet anticorps anti-AKR1C4 est un anticorps Lapin Polyclonal détectant AKR1C4 dans WB, ELISA et IF. Adapté pour Humain, Souris et Rat.

Aperçu rapide pour AKR1C4 anticorps (ABIN7111464)

Antigène: AKR1C4 (Aldo-keto Reductase Family 1 Member C4 (AKR1C4))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp AKR1C4 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Détail du produit anti-AKR1C4 anticorps

Fonction: AKR1C4 antibody

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: aldo-keto reductase family 1, member C4(chlordecone reductase, 3-alpha hydroxysteroid dehydrogenase, type I, dihydrodiol dehydrogenase 4)

Isotype: IgG

Information d'application

Indications d'application: WB: 1:1000-1:10000, IF: 1:10-1:100

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months

Date de péremption: 12 months

Détails sur AKR1C4

Antigène: AKR1C4 (Aldo-keto Reductase Family 1 Member C4 (AKR1C4))

Autre désignation: AKR1C4

Sujet:

Synonyms: Aldo-keto reductase family 1 member C4|3-alpha-hydroxysteroid dehydrogenase type I (3-alpha-HSD1)|3alpha-hydroxysteroid 3-dehydrogenase|Chlordecone reductase (CDR)|Dihydrodiol dehydrogenase 4 (DD-4, DD4)|HAKRA|AKR1C4|CHDR

Background: Catalyzes the transformation of the potent androgen dihydrotestosterone(DHT) into the less active form, 5-alpha-androstan-3-alpha,17-beta-diol(3-alpha-diol). Also has some 20-alpha-hydroxysteroid dehydrogenase activity. The biotransformation of the pesticide chlordecone(kepone) to its corresponding alcohol leads to increased biliary excretion of the pesticide and concomitant reduction of its neurotoxicity since bile is the major excretory route.

Poids moléculaire: 37 kDa

ID gène: 1109

UniProt: P17516

Pathways: Steroid Hormone Biosynthesis