ANKRD15 anticorps

N° du produit ABIN7111596

Cet anticorps anti-ANKRD15 est un anticorps Lapin Polyclonal détectant ANKRD15 dans WB, ELISA, IF et IHC. Adapté pour Humain, Souris et Rat.

Aperçu rapide pour ANKRD15 anticorps (ABIN7111596)

Antigène: ANKRD15 (Ankyrin Repeat Domain 15 (ANKRD15))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ANKRD15 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (IHC)

Détail du produit anti-ANKRD15 anticorps

Fonction: KANK1 antibody

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: KN motif and ankyrin repeat domains 1

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:2000, IHC: 1:20-1:200, IF: 1:20-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months

Date de péremption: 12 months

Détails sur ANKRD15

Antigène: ANKRD15 (Ankyrin Repeat Domain 15 (ANKRD15))

Autre désignation: KANK1

Sujet:

Synonyms: KN motif and ankyrin repeat domain-containing protein 1|Ankyrin repeat domain-containing protein 15|Kidney ankyrin repeat-containing protein|KANK1|ANKRD15|KANK|KIAA0172

Background: Involved in the control of cytoskeleton formation by regulating actin polymerization. Inhibits actin fiber formation and cell migration. Inhibits RhoA activity, the function involves phosphorylation through PI3K/Akt signaling and may depend on the competetive interaction with 14-3-3 adapter proteins to sequester them from active complexes. Inhibits the formation of lamellipodia but not of filopodia, the function may depend on the competetive interaction with BAIAP2 to block its association with activated RAC1. Inhibits fibronectin-mediated cell spreading, the function is partially mediated by BAIAP2. Inhibits neurite outgrowth. Involved in the establishment and persistence of cell polarity during directed cell movement in wound healing. In the nucleus, is involved in beta-catenin-dependent activation of transcription. Potential tumor suppressor for renal cell carcinoma.

Poids moléculaire: 150 kDa

ID gène: 23189

UniProt: Q14678

Pathways: Regulation of Actin Filament Polymerization