ATG4B anticorps

N° du produit ABIN7111893

Cet anticorps anti-ATG4B est un anticorps Lapin Polyclonal détectant ATG4B dans WB, ELISA, IHC et IP. Adapté pour Humain, Souris et Rat.

Aperçu rapide pour ATG4B anticorps (ABIN7111893)

Antigène: ATG4B (Autophagy related 4B Cysteine Peptidase (ATG4B))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ATG4B est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP)

Détail du produit anti-ATG4B anticorps

Fonction: ATG4B antibody

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: ATG4 autophagy related 4 homolog B

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:2000, IP: 1:500-1:2000 , IHC: 1:20-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months

Date de péremption: 12 months

Détails sur ATG4B

Antigène: ATG4B (Autophagy related 4B Cysteine Peptidase (ATG4B))

Autre désignation: ATG4B

Sujet:

Synonyms: Cysteine protease ATG4B|AUT-like 1 cysteine endopeptidase|Autophagy-related cysteine endopeptidase 1 (Autophagin-1)|Autophagy-related protein 4 homolog B (HsAPG4B, hAPG4B)|ATG4B|APG4B|AUTL1|KIAA0943

Background: Cysteine protease required for the cytoplasm to vacuole transport(Cvt) and autophagy. Cleaves the C-terminal amino acid of ATG8 family proteins MAP1LC3, GABARAPL1, GABARAPL2 and GABARAP, to reveal a C-terminal glycine. Exposure of the glycine at the C-terminus is essential for ATG8 proteins conjugation to phosphatidylethanolamine(PE) and insertion to membranes, which is necessary for autophagy. Has also an activity of delipidating enzyme for the PE-conjugated forms.

Poids moléculaire: 44 kDa

ID gène: 23192

UniProt: Q9Y4P1

Pathways: Autophagy