BVES anticorps

N° du produit ABIN7112013

Cet anticorps anti-BVES est un anticorps Lapin Polyclonal détectant BVES dans WB, ELISA et IHC. Adapté pour Humain, Souris et Rat.

Aperçu rapide pour BVES anticorps (ABIN7112013)

Antigène: BVES (Blood Vessel Epicardial Substance (BVES))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp BVES est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Détail du produit anti-BVES anticorps

Fonction: BVES antibody

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: blood vessel epicardial substance

Isotype: IgG

Information d'application

Indications d'application: WB: 1:100-1:1000, IHC: 1:20-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months

Date de péremption: 12 months

Détails sur BVES

Antigène: BVES (Blood Vessel Epicardial Substance (BVES))

Autre désignation: BVES

Sujet:

Synonyms: Blood vessel epicardial substance (hBVES)|Popeye domain-containing protein 1 (Popeye protein 1)|BVES|POP1|POPDC1

Background: Cell adhesion molecule involved in the establishment and/or maintenance of cell integrity. Involved in the formation and regulation of the tight junction(TJ) paracellular permeability barrier in epithelial cells(PubMed:16188940). Plays a role in VAMP3-mediated vesicular transport and recycling of different receptor molecules through its interaction with VAMP3. Plays a role in the regulation of cell shape and movement by modulating the Rho-family GTPase activity through its interaction with ARHGEF25/GEFT. Induces primordial adhesive contact and aggregation of epithelial cells in a Ca(2+)-independent manner. Also involved in striated muscle regeneration and repair and in the regulation of cell spreading(By similarity). Important for the maintenance of cardiac function. Plays a regulatory function in heart rate dynamics mediated, at least in part, through cAMP-binding and, probably, by increasing cell surface expression of the potassium channel KCNK2 and enhancing current density(PubMed:26642364). Is also a caveolae-associated protein important for the preservation of caveolae structural and functional integrity as well as for heart protection against ischemia injury.

Poids moléculaire: 41-70 kDa

ID gène: 11149

UniProt: Q8NE79