BMI1 anticorps (AA 1-326)

N° du produit ABIN7112015

L’anticorps Souris Monoclonal anti-BMI1 a été validé pour WB, IHC, ELISA, IF et IP. Il convient pour détecter BMI1 dans des échantillons de Humain et Souris.

Aperçu rapide pour BMI1 anticorps (AA 1-326) (ABIN7112015)

Antigène: BMI1 (BMI1 Polycomb Ring Finger Oncogene (BMI1))

Reactivité: Humain, Souris

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp BMI1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Immunoprecipitation (IP)

Clone: 8D5

Détail du produit anti-BMI1 anticorps

Épitope: AA 1-326

Fonction: BMI1 antibody

Purification: Protein A+G purification

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène:

Immunogen sequence: 1-326aa

Immunogen: BMI1 polycomb ring finger oncogene

Isotype: IgG1

Information d'application

Indications d'application: WB: 1:500-1:2000, IP: 1:500-1:2000, IHC: 1:20-1:200, IF: 1:10-1:100

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months

Date de péremption: 12 months

Détails sur BMI1

Antigène: BMI1 (BMI1 Polycomb Ring Finger Oncogene (BMI1))

Autre désignation: BMI1

Sujet:

Synonyms: Polycomb complex protein BMI-1|Polycomb group RING finger protein 4|RING finger protein 51|BMI1|PCGF4|RNF51

Background: Component of a Polycomb group(PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones, it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. In the PRC1 complex, it is required to stimulate the E3 ubiquitin-protein ligase activity of RNF2/RING2.

Poids moléculaire: 37 kDa

ID gène: 648

UniProt: P35226

Pathways: Cycle Cellulaire, Autophagy