CAMK2A anticorps (pThr286)

N° du produit ABIN7112188

Cet anticorps Lapin Polyclonal détecte spécifiquement CAMK2A dans WB et ELISA. Il présente une réactivité envers Humain, Souris et Rat.

Aperçu rapide pour CAMK2A anticorps (pThr286) (ABIN7112188)

Antigène: CAMK2A (Calcium/calmodulin-Dependent Protein Kinase II alpha (CAMK2A))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CAMK2A est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-CAMK2A anticorps

Épitope: pThr286

Fonction: Phospho-Camk2a antibody

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: calcium/calmodulin-dependent protein kinase II alpha

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months

Date de péremption: 12 months

Détails sur CAMK2A

Antigène: CAMK2A (Calcium/calmodulin-Dependent Protein Kinase II alpha (CAMK2A))

Autre désignation: Camk2a

Sujet:

Synonyms: Calcium/calmodulin-dependent protein kinase type II subunit alpha (CaM kinase II subunit alpha, CaMK-II subunit alpha)|CAMK2A|CAMKA|KIAA0968

Background: The product of this gene belongs to the serine/threonine protein kinases family, and to the Ca(2+)/calmodulin-dependent protein kinases subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. This calcium calmodulin-dependent protein kinase is composed of four different chains: alpha, beta, gamma, and delta. The alpha chain encoded by this gene is required for hippocampal long-term potentiation (LTP) and spatial learning. In addition to its calcium-calmodulin (CaM)-dependent activity, this protein can undergo autophosphorylation, resulting in CaM-independent activity. Two transcript variants encoding distinct isoforms have been identified for this gene.

Poids moléculaire: 54 kDa

UniProt: Q9UQM7

Pathways: Signalisation WNT, Interferon-gamma Pathway, Myometrial Relaxation and Contraction