CD320 anticorps (AA 80-282)

N° du produit ABIN7112479

Cet anticorps Lapin Polyclonal détecte spécifiquement CD320 dans WB, ELISA et IHC. Il présente une réactivité envers Humain et Souris.

Aperçu rapide pour CD320 anticorps (AA 80-282) (ABIN7112479)

Antigène: CD320 (CD320 Molecule (CD320))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CD320 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Détail du produit anti-CD320 anticorps

Épitope: AA 80-282

Fonction: CD320 antibody

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène:

Immunogen sequence: 80-282aa

Immunogen: CD320 molecule

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:1000, IHC: 1:20-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months

Date de péremption: 12 months

Détails sur CD320

Antigène: CD320 (CD320 Molecule (CD320))

Autre désignation: CD320

Sujet:

Synonyms: CD320 antigen|8D6 antigen|FDC-signaling molecule 8D6 (FDC-SM-8D6)|Transcobalamin receptor (TCblR)|CD320|8D6A

Background: CD320, also known as 8D6, 8D6A or TCblR, is a single-pass type I membrane protein containing 2 LDL-receptor class A domains. Expressed abundantly on follicular dendritic cells (FDCs), CD320 has been shown to enhance proliferation of germinal center (GC) B cells. It is the receptor for cellular uptake of transcobalamin-bound cobalamin. Defects in CD320 are the cause of methylmalonic aciduria type TCblR (MMATC). CD320 has a calculated molecular mass of 29 kDa. This antibody detects bands at 50-55 kDa and 60-70 kDa, probably caused by extensive complex glycosylation.

Poids moléculaire: 50-55 kDa, 60-70 kDa

ID gène: 51293

UniProt: Q9NPF0