CRCP anticorps
Aperçu rapide pour CRCP anticorps (ABIN7112634)
Antigène
Voir toutes CRCP AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Fonction
- CRCP antibody
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Purification
- Immunogen affinity purified
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Pureté
- ≥95 % as determined by SDS-PAGE
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Immunogène
- CGRP receptor component
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Isotype
- IgG
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Indications d'application
- WB: 1:1000-1:4000, IP: 1:500-1:2000, IHC: 1:20-1:200
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freeze / thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- -20°C for 12 months
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Date de péremption
- 12 months
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- CRCP (CGRP Receptor Component (CRCP))
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Autre désignation
- CRCP
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Sujet
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Synonyms: DNA-directed RNA polymerase III subunit RPC9 (RNA polymerase III subunit C9)|Calcitonin gene-related peptide-receptor component protein (CGRP-RCP, CGRP-receptor component protein, CGRPRCP, HsC17)|CRCP
Background: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. Plays a key role in sensing and limiting infection by intracellular bacteria and DNA viruses. Acts as nuclear and cytosolic DNA sensor involved in innate immune response. Can sense non-self dsDNA that serves as template for transcription into dsRNA. The non-self RNA polymerase III transcripts induce type I interferon and NF-Kappa-B through the RIG-I pathway(By similarity).
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Poids moléculaire
- 20 kDa
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ID gène
- 27297
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UniProt
- O75575
Antigène
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