COBRA1 anticorps
Aperçu rapide pour COBRA1 anticorps (ABIN7112923)
Antigène
Voir toutes COBRA1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
-
-
Fonction
- NELFB antibody
-
Purification
- Immunogen affinity purified
-
Pureté
- ≥95 % as determined by SDS-PAGE
-
Immunogène
- cofactor of BRCA1
-
Isotype
- IgG
-
-
-
-
Indications d'application
- WB: 1:500-1:2000, IP: 1:500-1:1000, IF: 1:10-1:100
-
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
-
Agent conservateur
- Sodium azide
-
Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Conseil sur la manipulation
- Avoid repeated freeze / thaw cycles.
-
Stock
- -20 °C
-
Stockage commentaire
- -20°C for 12 months
-
Date de péremption
- 12 months
-
-
- COBRA1 (Cofactor of BRCA1 (COBRA1))
-
Autre désignation
- NELFB
-
Sujet
-
Synonyms: Negative elongation factor B (NELF-B)|Cofactor of BRCA1|NELFB|COBRA1|KIAA1182
Background: Essential component of the NELF complex, a complex that negatively regulates the elongation of transcription by RNA polymerase II. The NELF complex, which acts via an association with the DSIF complex and causes transcriptional pausing, is counteracted by the P-TEFb kinase complex. May be able to induce chromatin unfolding.
-
Poids moléculaire
- 66 kDa
-
ID gène
- 25920
-
UniProt
- Q8WX92
Antigène
-