COPS4 anticorps

N° du produit ABIN7113044

Détail du produit anti-COPS4 anticorps

Antigène: COPS4 (COP9 Signalosome Subunit 4 (COPS4))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp COPS4 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP)

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: COP9 constitutive photomorphogenic homolog subunit 4(Arabidopsis)

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:2000, IP: 1:200-1:1000, IHC: 1:20-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Date de péremption: 12 months

Détails sur COPS4

Antigène: COPS4 (COP9 Signalosome Subunit 4 (COPS4))

Autre désignation: COPS4 (COPS4 Produits)

Synonymes: anticorps CG8725, anticorps CH4, anticorps Cops4, anticorps Csn4, anticorps DCH4, anticorps Dch4, anticorps Dmel\\CG8725, anticorps csn4, anticorps l(2)k08018, anticorps COPS4, anticorps SGN4, anticorps DKFZp459H0324, anticorps AW208976, anticorps D5Ertd774e, anticorps fc90c08, anticorps wu:fc90c08, anticorps zgc:77137, anticorps ATS4, anticorps CONSTITUTIVE PHOTOMORPHOGENIC 14, anticorps CONSTITUTIVE PHOTOMORPHOGENIC 8, anticorps COP14, anticorps COP9 SIGNALOSOME SUBUNIT 4, anticorps CSN4, anticorps EMB134, anticorps EMBRYO DEFECTIVE 134, anticorps FUS4, anticorps FUS8, anticorps FUSCA 4, anticorps FUSCA 8, anticorps MBD2.17, anticorps MBD2_17, anticorps COS41.8, anticorps COP9 signalosome subunit 4, anticorps COP9 signalosome complex subunit 4, anticorps COP9 constitutive photomorphogenic homolog subunit 4 (Arabidopsis), anticorps Proteasome component (PCI) domain protein, anticorps COP9 signalosome subunit 4 L homeolog, anticorps CSN4, anticorps COPS4, anticorps CpipJ_CPIJ000966, anticorps csn4, anticorps Cops4, anticorps cops4, anticorps COP8, anticorps cops4.L, anticorps csn-4

Sujet: Synonyms:CSN4 Background:Component of the COP9 signalosome complex(CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin(Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2. Also involved in the deneddylation of non-cullin subunits such as STON2. The complex is also involved in phosphorylation of p53/TP53, c-jun/JUN, IkappaBalpha/NFKBIA, ITPK1, IRF8/ICSBP and SNAPIN, possibly via its association with CK2 and PKD kinases. CSN-dependent phosphorylation of TP53 and JUN promotes and protects degradation by the Ubl system, respectively.

Poids moléculaire: 40, 46 kDa

ID gène: 51138

UniProt: Q9BT78

Pathways: Cycle Cellulaire