Exportin 2 anticorps

N° du produit ABIN7113096

Détail du produit anti-Exportin 2 anticorps

Antigène: Exportin 2 (CSE1L) (CSE1 Chromosome Segregation 1-Like (CSE1L))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Exportin 2 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: CSE1 chromosome segregation 1-like(yeast)

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:2000, IHC: 1:20-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Date de péremption: 12 months

Détails sur Exportin 2

Antigène: Exportin 2 (CSE1L) (CSE1 Chromosome Segregation 1-Like (CSE1L))

Autre désignation: CSE1L (CSE1L Produits)

Synonymes: anticorps BcDNA:LD14270, anticorps CAS, anticorps CG13281, anticorps Dcas, anticorps Dmel\\CG13281, anticorps cas, anticorps dcas, anticorps l(2)k03902, anticorps CSE1L, anticorps XPO2, anticorps Exportin-2, anticorps DKFZp459E1929, anticorps 2610100P18Rik, anticorps AA407533, anticorps Capts, anticorps Cas, anticorps Xpo2, anticorps xpo2, anticorps CSE1, anticorps CAS/CSE1 segregation protein, anticorps chromosome segregation 1 like, anticorps exportin-2, anticorps chromosome segregation 1-like (S. cerevisiae), anticorps CSE1 chromosome segregation 1-like (yeast), anticorps CSE1 chromosome segregation 1-like L homeolog, anticorps Cas, anticorps CSE1L, anticorps LOC100542094, anticorps cse1l, anticorps Cse1l, anticorps cse1l.L

Sujet: Synonyms:CAS, XPO2 Background:Export receptor for importin-alpha. Mediates importin-alpha re-export from the nucleus to the cytoplasm after import substrates(cargos) have been released into the nucleoplasm. In the nucleus binds cooperatively to importin-alpha and to the GTPase Ran in its active GTP-bound form. Docking of this trimeric complex to the nuclear pore complex(NPC) is mediated through binding to nucleoporins. Upon transit of a nuclear export complex into the cytoplasm, disassembling of the complex and hydrolysis of Ran-GTP to Ran-GDP(induced by RANBP1 and RANGAP1, respectively) cause release of the importin-alpha from the export receptor. CSE1L/XPO2 then return to the nuclear compartment and mediate another round of transport. The directionality of nuclear export is thought to be conferred by an asymmetric distribution of the GTP-and GDP-bound forms of Ran between the cytoplasm and nucleus.

Poids moléculaire: 100-110 kDa

ID gène: 1434

UniProt: P55060

Pathways: Protein targeting to Nucleus