DLL4 anticorps
Aperçu rapide pour DLL4 anticorps (ABIN7113410)
Antigène
Voir toutes DLL4 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
-
-
Fonction
- DLL4 antibody
-
Purification
- Immunogen affinity purified
-
Pureté
- ≥95 % as determined by SDS-PAGE
-
Immunogène
- delta-like 4(Drosophila)
-
Isotype
- IgG
-
-
-
-
Indications d'application
- WB: 1:500-1:2000, IP: 1:200-1:2000
-
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
-
Agent conservateur
- Sodium azide
-
Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Conseil sur la manipulation
- Avoid repeated freeze / thaw cycles.
-
Stock
- -20 °C
-
Stockage commentaire
- -20°C for 12 months
-
Date de péremption
- 12 months
-
-
- DLL4 (delta-Like 4 (DLL4))
-
Autre désignation
- DLL4
-
Sujet
-
Synonyms: Delta-like protein 4|Drosophila Delta homolog 4 (Delta4)|DLL4
Background: Involved in the Notch signaling pathway as Notch ligand(PubMed:11134954). Activates NOTCH1 and NOTCH4. Involved in angiogenesis, negatively regulates endothelial cell proliferation and migration and angiogenic sprouting(PubMed:20616313). Essential for retinal progenitor proliferation. Required for suppressing rod fates in late retinal progenitors as well as for proper generation of other retinal cell types(By similarity). During spinal cord neurogenesis, inhibits V2a interneuron fate(PubMed:17728344).
-
Poids moléculaire
- 75-80 kDa
-
ID gène
- 54567
-
UniProt
- Q9NR61
-
Pathways
- Signalisation Notch
Antigène
-