DENND1A anticorps
Aperçu rapide pour DENND1A anticorps (ABIN7113415)
Antigène
Voir toutes DENND1A AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Fonction
- DENND1A antibody
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Purification
- Immunogen affinity purified
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Pureté
- ≥95 % as determined by SDS-PAGE
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Immunogène
- DENN/MADD domain containing 1A
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Isotype
- IgG
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Indications d'application
- WB: 1:500-1:2000, IF: 1:20-1:200
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freeze / thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- -20°C for 12 months
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Date de péremption
- 12 months
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- DENND1A (DENN/MADD Domain Containing 1A (DENND1A))
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Autre désignation
- DENND1A
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Sujet
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Synonyms: DENN domain-containing protein 1A|Connecdenn 1 (Connecdenn)|Protein FAM31A|DENND1A|FAM31A|KIAA1608
Background: Guanine nucleotide exchange factor(GEF) regulating clathrin-mediated endocytosis through RAB35 activation. Promotes the exchange of GDP to GTP, converting inactive GDP-bound RAB35 into its active GTP-bound form. Regulates clathrin-mediated endocytosis of synaptic vesicles and mediates exit from early endosomes(PubMed:20154091, PubMed:20937701). Binds phosphatidylinositol-phosphates(PtdInsPs), with some preference for PtdIns(3)P(By similarity).
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Poids moléculaire
- 111 kDa, 64 kDa
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ID gène
- 57706
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UniProt
- Q8TEH3
Antigène
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