DBNL anticorps

N° du produit ABIN7113623

L’anticorps Lapin Polyclonal anti-DBNL a été validé pour WB, ELISA, IF, IHC et IP. Il convient pour détecter DBNL dans des échantillons de Humain, Souris et Rat.

Aperçu rapide pour DBNL anticorps (ABIN7113623)

Antigène: DBNL (Drebrin-Like (DBNL))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DBNL est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (IHC), Immunoprecipitation (IP)

Détail du produit anti-DBNL anticorps

Fonction: DBNL antibody

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: drebrin-like

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:2000, IP: 1:200-1:1000, IHC: 1:20-1:200, IF: 1:20-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months

Date de péremption: 12 months

Détails sur DBNL

Antigène: DBNL (Drebrin-Like (DBNL))

Autre désignation: DBNL

Sujet:

Synonyms: Drebrin-like protein|Cervical SH3P7|Cervical mucin-associated protein|Drebrin-F|HPK1-interacting protein of 55 kDa (HIP-55)|SH3 domain-containing protein 7|DBNL|CMAP|SH3P7

Background: Adapter protein that binds F-actin and DNM1, and thereby plays a role in receptor-mediated endocytosis. Plays a role in the reorganization of the actin cytoskeleton, formation of cell projections, such as neurites, in neuron morphogenesis and synapse formation via its interaction with WASL and COBL. Does not bind G-actin and promote actin polymerization by itself. Required for the formation of organized podosome rosettes(By similarity). May act as a common effector of antigen receptor-signaling pathways in leukocytes. Acts as a key component of the immunological synapse that regulates T-cell activation by bridging TCRs and the actin cytoskeleton to gene activation and endocytic processes.

Poids moléculaire: 55 kDa

ID gène: 28988

UniProt: Q9UJU6

Pathways: TCR Signaling, Regulation of Actin Filament Polymerization