DBNL anticorps

N° du produit ABIN7113623

Détail du produit anti-DBNL anticorps

Antigène: DBNL (Drebrin-Like (DBNL))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DBNL est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunofluorescence (IF)

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: drebrin-like

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:2000, IP: 1:200-1:1000, IHC: 1:20-1:200, IF: 1:20-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Date de péremption: 12 months

Détails sur DBNL

Antigène: DBNL (Drebrin-Like (DBNL))

Autre désignation: DBNL (DBNL Produits)

Synonymes: anticorps ABP1, anticorps HIP-55, anticorps HIP55, anticorps SH3P7, anticorps Abp1, anticorps mAbp1, anticorps Sh3p7, anticorps abp1, anticorps dbnl-B, anticorps DBNL, anticorps DKFZp459C0939, anticorps drebrin like, anticorps drebrin-like, anticorps drebrin like S homeolog, anticorps drebrin 1, anticorps DBNL, anticorps Dbnl, anticorps dbnl.S, anticorps LOC100148204, anticorps DBN1

Sujet: Synonyms:CMAP, SH3P7 Background:Adapter protein that binds F-actin and DNM1, and thereby plays a role in receptor-mediated endocytosis. Plays a role in the reorganization of the actin cytoskeleton, formation of cell projections, such as neurites, in neuron morphogenesis and synapse formation via its interaction with WASL and COBL. Does not bind G-actin and promote actin polymerization by itself. Required for the formation of organized podosome rosettes(By similarity). May act as a common effector of antigen receptor-signaling pathways in leukocytes. Acts as a key component of the immunological synapse that regulates T-cell activation by bridging TCRs and the actin cytoskeleton to gene activation and endocytic processes.

Poids moléculaire: 55 kDa

ID gène: 28988

UniProt: Q9UJU6

Pathways: TCR Signaling, Regulation of Actin Filament Polymerization