E2F4 anticorps
Aperçu rapide pour E2F4 anticorps (ABIN7113686)
Antigène
Voir toutes E2F4 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
-
-
Fonction
- E2F4 antibody
-
Purification
- Immunogen affinity purified
-
Pureté
- ≥95 % as determined by SDS-PAGE
-
Immunogène
- E2F transcription factor 4, p107/p130-binding
-
Isotype
- IgG
-
-
-
-
Indications d'application
- WB: 1:500-1:2000, IP: 1:200-1:1000, IHC: 1:20-1:200
-
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
-
Agent conservateur
- Sodium azide
-
Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Conseil sur la manipulation
- Avoid repeated freeze / thaw cycles.
-
Stock
- -20 °C
-
Stockage commentaire
- -20°C for 12 months
-
Date de péremption
- 12 months
-
-
- E2F4 (E2F Transcription Factor 4, P107/p130-Binding (E2F4))
-
Autre désignation
- E2F4
-
Sujet
-
Synonyms: Transcription factor E2F4 (E2F-4)|E2F4
Background: Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The DRTF1/E2F complex functions in the control of cell-cycle progression from G1 to S phase. E2F4 binds with high affinity to RBL1 and RBL2. In some instances can also bind RB1. Specifically required for multiciliate cell differentiation: together with MCIDAS and E2F5, binds and activate genes required for centriole biogenesis.
-
Poids moléculaire
- 60-70 kDa
-
ID gène
- 1874
-
UniProt
- Q16254
-
Pathways
- Cycle Cellulaire, Mitotic G1-G1/S Phases, Regulation of Cell Size
Antigène
-