RAD18 anticorps

N° du produit ABIN7113695

L’anticorps Lapin Polyclonal anti-RAD18 a été validé pour WB, ELISA, IHC et IF. Il convient pour détecter RAD18 dans des échantillons de Humain, Rat et Souris.

Aperçu rapide pour RAD18 anticorps (ABIN7113695)

Antigène: RAD18 (E3 ubiquitin-protein ligase RAD18 (RAD18))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RAD18 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Détail du produit anti-RAD18 anticorps

Fonction: RAD18 antibody

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: RAD18 homolog

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500 - 1:2000, IHC: 1:50 - 1:200, IF: 1:50 - 1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months

Date de péremption: 12 months

Détails sur RAD18

Antigène: RAD18 (E3 ubiquitin-protein ligase RAD18 (RAD18))

Autre désignation: RAD18

Sujet:

Synonyms: E3 ubiquitin-protein ligase RAD18|Postreplication repair protein RAD18 (hHR18, hRAD18)|RING finger protein 73|RING-type E3 ubiquitin transferase RAD18|RAD18|RNF73

Background: The protein encoded by this gene is highly similar to S. cerevisiae DNA damage repair protein Rad18. Yeast Rad18 functions through its interaction with Rad6, which is an ubiquitin-conjugating enzyme required for post-replication repair of damaged DNA. Similar to its yeast counterpart, this protein is able to interact with the human homolog of yeast Rad6 protein through a conserved ring-finger motif. Mutation of this motif results in defective replication of UV-damaged DNA and hypersensitivity to multiple mutagens.

Poids moléculaire: 80 kDa

ID gène: 56852

UniProt: Q9NS91