Ensa anticorps
Aperçu rapide pour Ensa anticorps (ABIN7113813)
Antigène
Voir toutes Ensa (ENSA) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Fonction
- ENSA antibody
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Purification
- Immunogen affinity purified
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Pureté
- ≥95 % as determined by SDS-PAGE
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Immunogène
- endosulfine alpha
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Isotype
- IgG
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Indications d'application
- WB: 1:500-1:2000, IHC: 1:20-1:200
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freeze / thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- -20°C for 12 months
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Date de péremption
- 12 months
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- Ensa (ENSA) (Endosulfine alpha (ENSA))
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Autre désignation
- ENSA
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Sujet
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Synonyms: Alpha-endosulfine|ARPP-19e|ENSA
Background: Protein phosphatase inhibitor that specifically inhibits protein phosphatase 2A(PP2A) during mitosis. When phosphorylated at Ser-67 during mitosis, specifically interacts with PPP2R2D(PR55-delta) and inhibits its activity, leading to inactivation of PP2A, an essential condition to keep cyclin-B1-CDK1 activity high during M phase(By similarity). Also acts as a stimulator of insulin secretion by interacting with sulfonylurea receptor(ABCC8), thereby preventing sulfonylurea from binding to its receptor and reducing K(ATP) channel currents.
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Poids moléculaire
- 19 kDa
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ID gène
- 2029
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UniProt
- O43768
Antigène
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