EPH Receptor B4 anticorps

N° du produit ABIN7113852

Cet anticorps anti-EPH Receptor B4 est un anticorps Lapin Polyclonal détectant EPH Receptor B4 dans WB, ELISA, IHC et FACS. Adapté pour Humain, Souris et Rat.

Aperçu rapide pour EPH Receptor B4 anticorps (ABIN7113852)

Antigène: EPH Receptor B4 (EPHB4)

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp EPH Receptor B4 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS)

Détail du produit anti-EPH Receptor B4 anticorps

Fonction: EPHB4 antibody

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène:

Immunogen sequence: Extracellular,300-539AA

Immunogen: EPH receptor B4

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:5000, IHC: 1:20-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months

Date de péremption: 12 months

Détails sur EPH Receptor B4

Antigène: EPH Receptor B4 (EPHB4)

Autre désignation: EPHB4

Sujet:

Synonyms: Ephrin type-B receptor 4|Hepatoma transmembrane kinase|Tyrosine-protein kinase TYRO11|EPHB4|HTK|MYK1|TYRO11

Background: Receptor tyrosine kinase which binds promiscuously transmembrane ephrin-B family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Together with its cognate ligand/functional ligand EFNB2 plays a central role in heart morphogenesis and angiogenesis through regulation of cell adhesion and cell migration. EPHB4-mediated forward signaling controls cellular repulsion and segregation form EFNB2-expressing cells. Plays also a role in postnatal blood vessel remodeling, morphogenesis and permeability and is thus important in the context of tumor angiogenesis.

Poids moléculaire: 110 kDa

ID gène: 2050

UniProt: P54760

Pathways: Signalisation RTK