EIF3B anticorps

N° du produit ABIN7113952

Cet anticorps Lapin Polyclonal détecte spécifiquement EIF3B dans WB et ELISA. Il présente une réactivité envers Humain, Souris et Rat.

Aperçu rapide pour EIF3B anticorps (ABIN7113952)

Antigène: EIF3B (Eukaryotic Translation Initiation Factor 3, Subunit B (EIF3B))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp EIF3B est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-EIF3B anticorps

Fonction: EIF3B antibody

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: eukaryotic translation initiation factor 3, subunit B

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500 - 1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months

Date de péremption: 12 months

Détails sur EIF3B

Antigène: EIF3B (Eukaryotic Translation Initiation Factor 3, Subunit B (EIF3B))

Autre désignation: EIF3B

Sujet:

Synonyms: Eukaryotic translation initiation factor 3 subunit B (eIF3b)|Eukaryotic translation initiation factor 3 subunit 9|Prt1 homolog (hPrt1)|eIF-3-eta|eIF3 p110|eIF3 p116|EIF3B|EIF3S9

Background: Component of the eukaryotic translation initiation factor 3(eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex(43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. (Microbial infection) In case of FCV infection, plays a role in the ribosomal termination-reinitiation event leading to the translation of VP2(PubMed:18056426).

Poids moléculaire: 120 kDa

ID gène: 8662

UniProt: P55884

Pathways: Ribonucleoprotein Complex Subunit Organization