EIF3B anticorps (AA 100-350)

N° du produit ABIN6140053

Détail du produit anti-EIF3B anticorps

Antigène: EIF3B (Eukaryotic Translation Initiation Factor 3, Subunit B (EIF3B))

Épitope: AA 100-350

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp EIF3B est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF)

Séquence: PVPAQGEAPG EQARDERSDS RAQAVSEDAG GNEGRAAEAE PRALENGDAD EPSFSDPEDF VDDVSEEELL GDVLKDRPQE ADGIDSVIVV DNVPQVGPDR LEKLKNVIHK IFSKFGKITN DFYPEEDGKT KGYIFLEYAS PAHAVDAVKN ADGYKLDKQH TFRVNLFTDF DKYMTISDEW DIPEKQPFKD LGNLRYWLEE AECRDQYSVI FESGDRTSIF WNDVKDPVSI EERARWTETY VRWSPKGTYL A

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 100-350 of human eIF3B (NP_003742.2).

Isotype: IgG

Information d'application

Indications d'application: WB,1:1000 - 1:2000,IF,1:50 - 1:200

Commentaires:

HIGH QUALITY

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur EIF3B

Antigène: EIF3B (Eukaryotic Translation Initiation Factor 3, Subunit B (EIF3B))

Autre désignation: EIF3B (EIF3B Produits)

Synonymes: anticorps EIF3-ETA, anticorps EIF3-P110, anticorps EIF3-P116, anticorps EIF3S9, anticorps PRT1, anticorps AL033316, anticorps AL033334, anticorps AL033369, anticorps AW208965, anticorps D5Wsu45e, anticorps Eif3s9, anticorps eif3-eta, anticorps eif3-p110, anticorps eif3-p116, anticorps eif3s9, anticorps prt1, anticorps ATEIF3B-2, anticorps EIF3B, anticorps EUKARYOTIC TRANSLATION INITIATION FACTOR 3B, anticorps F18A17.30, anticorps F18A17_30, anticorps eukaryotic translation initiation factor 3B-2, anticorps DDBDRAFT_0218512, anticorps DDBDRAFT_0233929, anticorps DDB_0218512, anticorps DDB_0233929, anticorps eIF-3-eta, anticorps eif3b, anticorps wu:fc17c01, anticorps GB10123, anticorps eIF3b, anticorps AO090005000892, anticorps CaO19.6584, anticorps eIF3 p90, anticorps eukaryotic translation initiation factor 3 subunit B, anticorps eukaryotic translation initiation factor 3, subunit B, anticorps eukaryotic translation initiation factor 3B-2, anticorps eukaryotic initiation factor, anticorps RNA recognition motif-containing protein RRM, anticorps eukaryotic translation initiation factor 3b, anticorps eukaryotic translation initiation factor 3 subunit B L homeolog, anticorps eukaryotic translation initiation factor 3, subunit Ba, anticorps eukaryotic translation initiation factor 3 subunit 9, anticorps translation initiation factor eIF-3 subunit 9, anticorps Eukaryotic translation initiation factor 3 subunit B, anticorps translation initiation factor eIF3 subunit b, anticorps EIF3B, anticorps Eif3b, anticorps eif3b, anticorps EIF3B-2, anticorps eIF3s9, anticorps eif3B, anticorps eif3b.L, anticorps eif3ba, anticorps LOC410100, anticorps eIF3-S9, anticorps AOR_1_1564174, anticorps VDBG_02490, anticorps PGTG_13070, anticorps Tsp_02250, anticorps eif-3.B, anticorps PRT1

Sujet: RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3 complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC. The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation, including cell cycling, differentiation and apoptosis, and uses different modes of RNA stem-loop binding to exert either translational activation or repression.,EIF3B,EIF3-ETA,EIF3-P110,EIF3-P116,EIF3S9,PRT1,Epigenetics & Nuclear Signaling,EIF3B

Poids moléculaire: 92 kDa/99 kDa

ID gène: 8662

UniProt: P55884

Pathways: Ribonucleoprotein Complex Subunit Organization