EIF3L anticorps

N° du produit ABIN7113957

Cet anticorps anti-EIF3L est un anticorps Lapin Polyclonal détectant EIF3L dans WB et ELISA. Adapté pour Humain, Souris et Rat.

Aperçu rapide pour EIF3L anticorps (ABIN7113957)

Antigène: EIF3L (Eukaryotic Translation Initiation Factor 3, Subunit L (EIF3L))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp EIF3L est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-EIF3L anticorps

Fonction: EIF3L antibody

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: eukaryotic translation initiation factor 3, subunit L

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months

Date de péremption: 12 months

Détails sur EIF3L

Antigène: EIF3L (Eukaryotic Translation Initiation Factor 3, Subunit L (EIF3L))

Autre désignation: EIF3L

Sujet:

Synonyms: Eukaryotic translation initiation factor 3 subunit L (eIF3l)|Eukaryotic translation initiation factor 3 subunit 6-interacting protein|Eukaryotic translation initiation factor 3 subunit E-interacting protein|EIF3L|EIF3EIP|EIF3S6IP

Background: Component of the eukaryotic translation initiation factor 3(eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex(43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. In case of FCV infection, plays a role in the ribosomal termination-reinitiation event leading to the translation of VP2(PubMed:18056426).

Poids moléculaire: 67 kDa

ID gène: 51386

UniProt: Q9Y262

Pathways: Ribonucleoprotein Complex Subunit Organization