EIF3L anticorps (AA 1-230)

N° du produit ABIN6140074

Détail du produit anti-EIF3L anticorps

Antigène: EIF3L (Eukaryotic Translation Initiation Factor 3, Subunit L (EIF3L))

Épitope: AA 1-230

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp EIF3L est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Séquence: MSYPADDYES EAAYDPYAYP SDYDMHTGDP KQDLAYERQY EQQTYQVIPE VIKNFIQYFH KTVSDLIDQK VYELQASRVS SDVIDQKVYE IQDIYENSWT KLTERFFKNT PWPEAEAIAP QVGNDAVFLI LYKELYYRHI YAKVSGGPSL EQRFESYYNY CNLFNYILNA DGPAPLELPN QWLWDIIDEF IYQFQSFSQY RCKTAKKSEE EIDFLRSNPK IWNVHSVLNV

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 1-230 of human EIF3L (NP_057175.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:1000 - 1:4000,IHC,1:50 - 1:200

Commentaires:

HIGH QUALITY

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur EIF3L

Antigène: EIF3L (Eukaryotic Translation Initiation Factor 3, Subunit L (EIF3L))

Autre désignation: EIF3L (EIF3L Produits)

Synonymes: anticorps wu:fb66c05, anticorps zgc:64147, anticorps EIF3EIP, anticorps EIF3S11, anticorps EIF3S6IP, anticorps HSPC021, anticorps HSPC025, anticorps MSTP005, anticorps 0610011H21Rik, anticorps D15N1e, anticorps Eif3eip, anticorps Eif3ip, anticorps Eif3s6ip, anticorps HSP-66Y, anticorps PAF67, anticorps eif3eip, anticorps eif3s6ip, anticorps eukaryotic translation initiation factor 3, subunit 6 interacting protein, anticorps eukaryotic translation initiation factor 3 subunit L, anticorps eukaryotic translation initiation factor 3, subunit L, anticorps eukaryotic translation initiation factor 3 subunit L L homeolog, anticorps eif3s6ip, anticorps EIF3L, anticorps Eif3l, anticorps eif3l.L

Sujet: Component of the eukaryotic translation initiation factor 3 (eIF-3 complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC. The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation, including cell cycling, differentiation and apoptosis, and uses different modes of RNA stem-loop binding to exert either translational activation or repression.,EIF3L,EIF3EIP,EIF3S11,EIF3S6IP,HSPC021,HSPC025,MSTP005,Epigenetics & Nuclear Signaling,EIF3L

Poids moléculaire: 61 kDa/66 kDa

ID gène: 51386

UniProt: Q9Y262

Pathways: Ribonucleoprotein Complex Subunit Organization