Eukaryotic Translation Initiation Factor 3, Subunit M (EIF3M) (AA 1-374) anticorps

N° du produit ABIN7113959

L’anticorps Souris Monoclonal anti- a été validé pour WB, ELISA et IF. Il convient pour détecter dans des échantillons de Humain.

Aperçu rapide pour Eukaryotic Translation Initiation Factor 3, Subunit M (EIF3M) (AA 1-374) anticorps (ABIN7113959)

Antigène: Eukaryotic Translation Initiation Factor 3, Subunit M (EIF3M)

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Inconjugué

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Clone: 1A4

Détail du produit

Épitope: AA 1-374

Fonction: EIF3M antibody

Purification: Protein A+G purification

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène:

Immunogen sequence: 1-374aa

Immunogen: eukaryotic translation initiation factor 3, subunit M

Isotype: IgG1

Information d'application

Indications d'application: WB: 1:500-1:2000, IF: 1:10-1:100

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months

Date de péremption: 12 months

Détail du antigène

Antigène: Eukaryotic Translation Initiation Factor 3, Subunit M (EIF3M)

Autre désignation: EIF3M

Sujet:

Synonyms: Eukaryotic translation initiation factor 3 subunit M (eIF3m)|Fetal lung protein B5 (hFL-B5)|PCI domain-containing protein 1|EIF3M|HFLB5|PCID1

Background: Component of the eukaryotic translation initiation factor 3(eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex(43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. May favor virus entry in case of infection with herpes simplex virus 1(HSV1) or herpes simplex virus 2(HSV2).

Poids moléculaire: 43 kDa

ID gène: 10480

UniProt: Q7L2H7

Pathways: Ribonucleoprotein Complex Subunit Organization