Exportin 7 anticorps

N° du produit ABIN7114023

Cet anticorps anti-Exportin 7 est un anticorps Lapin Polyclonal détectant Exportin 7 dans WB et ELISA. Adapté pour Humain, Souris et Rat.

Aperçu rapide pour Exportin 7 anticorps (ABIN7114023)

Antigène: Exportin 7 (XPO7)

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Exportin 7 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-Exportin 7 anticorps

Fonction: XPO7 antibody

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: exportin 7

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:5000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months

Date de péremption: 12 months

Détails sur Exportin 7

Antigène: Exportin 7 (XPO7)

Autre désignation: XPO7

Sujet:

Synonyms: Exportin-7 (Exp7)|Ran-binding protein 16|XPO7|KIAA0745|RANBP16

Background: Mediates the nuclear export of proteins(cargos) with broad substrate specificity. In the nucleus binds cooperatively to its cargo and to the GTPase Ran in its active GTP-bound form. Docking of this trimeric complex to the nuclear pore complex(NPC) is mediated through binding to nucleoporins. Upon transit of a nuclear export complex into the cytoplasm, disassembling of the complex and hydrolysis of Ran-GTP to Ran-GDP(induced by RANBP1 and RANGAP1, respectively) cause release of the cargo from the export receptor. XPO7 then return to the nuclear compartment and mediate another round of transport. The directionality of nuclear export is thought to be conferred by an asymmetric distribution of the GTP-and GDP-bound forms of Ran between the cytoplasm and nucleus.

Poids moléculaire: 100 kDa

ID gène: 23039

UniProt: Q9UIA9