GPR161 anticorps

N° du produit ABIN7114407

Cet anticorps anti-GPR161 est un anticorps Lapin Polyclonal détectant GPR161 dans WB, ELISA et IHC. Adapté pour Humain, Souris et Rat.

Aperçu rapide pour GPR161 anticorps (ABIN7114407)

Antigène: GPR161 (G Protein-Coupled Receptor 161 (GPR161))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GPR161 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Détail du produit anti-GPR161 anticorps

Fonction: GPR161 antibody

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: G protein-coupled receptor 161

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:2000, IHC: 1:20-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months

Date de péremption: 12 months

Détails sur GPR161

Antigène: GPR161 (G Protein-Coupled Receptor 161 (GPR161))

Autre désignation: GPR161

Sujet:

Synonyms: G-protein coupled receptor 161|G-protein coupled receptor RE2|GPR161

Background: Key negative regulator of Shh signaling, which promotes the processing of GLI3 into GLI3R during neural tube development. Recruited by TULP3 and the IFT-A complex to primary cilia and acts as a regulator of the PKA-dependent basal repression machinery in Shh signaling by increasing cAMP levels, leading to promote the PKA-dependent processing of GLI3 into GLI3R and repress the Shh signaling. In presence of SHH, it is removed from primary cilia and is internalized into recycling endosomes, preventing its activity and allowing activation of the Shh signaling. Its ligand is unknown(By similarity).

Poids moléculaire: 70 kDa

ID gène: 23432

UniProt: Q8N6U8

Pathways: cAMP Metabolic Process