GPSM1 anticorps

N° du produit ABIN7114427

L’anticorps anti-GPSM1 Polyclonal produit chez le Lapin a été validé pour ELISA, WB, IHC et IF. Il convient pour la détection de GPSM1 dans des échantillons provenant de Humain, Souris et Rat. }

Aperçu rapide pour GPSM1 anticorps (ABIN7114427)

Antigène: GPSM1 (G-Protein Signaling Modulator 1 (GPSM1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GPSM1 est non-conjugé

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Détail du produit anti-GPSM1 anticorps

Fonction: GPSM1 antibody

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: G-protein signaling modulator 1(AGS3-like, C. elegans)

Isotype: IgG

Information d'application

Indications d'application: WB: 1:200-1:2000, IF: 1:10-1:100, IHC: 1:20-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months

Date de péremption: 12 months

Détails sur GPSM1

Antigène: GPSM1 (G-Protein Signaling Modulator 1 (GPSM1))

Autre désignation: GPSM1

Sujet:

Synonyms: G-protein-signaling modulator 1|Activator of G-protein signaling 3|GPSM1|AGS3

Background: GPSM1, also named as AGS3, is a receptor-independent G protein activator that has been implicated in multiple biological events such as brain development, neuroplasticity and addiction, cardiac function, Golgi structure/function, macroautophagy and metabolism. It contains seven tetratricopeptide repeats in its N-terminal half and four G-protein regulatory(GPR) motifs in its C-terminal half. It has been shown that AGS3 could regulate the orientation of the mitotic spindle, cAMP production, membrane protein transport, and asymmetric cell division by binding preferentially to inactive Gai/o subunits complexed with guanine dinucleotide phosphate(GDP) at multiple G-protein regulatory or GoLoco motif repeats. It also plays an important anti-apoptotic role through enhancing the phosphorylation of cyclic AMP response element-binding protein(p-CREB).

Poids moléculaire: 72 kDa

ID gène: 26086

UniProt: Q86YR5

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling