GSDMD anticorps (AA 276-484)

N° du produit ABIN7114492

Cet anticorps Lapin Polyclonal détecte spécifiquement GSDMD dans WB, ELISA, IF et IHC. Il présente une réactivité envers Humain, Souris et Rat.

Aperçu rapide pour GSDMD anticorps (AA 276-484) (ABIN7114492)

Antigène: GSDMD (Gasdermin D (GSDMD))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GSDMD est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (IHC)

Détail du produit anti-GSDMD anticorps

Épitope: AA 276-484

Fonction: GSDMD antibody

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène:

Immunogen sequence: 276-484aa

Immunogen: gasdermin D

Isotype: IgG

Information d'application

Indications d'application: WB: 1:200-1:2000, IHC: 1:20-1:200, IF: 1:10-1:100

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months

Date de péremption: 12 months

Détails sur GSDMD

Antigène: GSDMD (Gasdermin D (GSDMD))

Autre désignation: GSDMD

Sujet:

Synonyms: Gasdermin-D|Gasdermin domain-containing protein 1|Gasdermin-D, C-terminal (GSDMD-CT, hGSDMD-CTD)|Gasdermin-D, p13|Gasdermin-D, 13 kDa (13 kDa GSDMD)|Gasdermin-D, p40|GSDMD|DFNA5L|GSDMDC1

Background: GSDMD is a member of the gasdermin family. Members of this family appear to play a role in regulation of epithelial proliferation. GSDMD has been suggested to act as a tumor suppressor. Recently, GSDMD is identified as a new component of inflammasomes, and it is an executor of pyroptosis and required for interleukin-1β secretion. Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death.

Poids moléculaire: 50-53 kDa

ID gène: 79792

UniProt: P57764

Pathways: Inflammasome