GSTa2 anticorps

N° du produit ABIN7114646

L’anticorps Lapin Polyclonal anti-GSTa2 a été validé pour WB, IHC et ELISA. Il convient pour détecter GSTa2 dans des échantillons de Humain, Souris et Rat.

Aperçu rapide pour GSTa2 anticorps (ABIN7114646)

Antigène: GSTa2 (Glutathione S-Transferase alpha 2 (GSTa2))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GSTa2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Détail du produit anti-GSTa2 anticorps

Fonction: GSTA2 antibody

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: glutathione S-transferase alpha 2

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500 - 1:2000, IHC: 1:50 - 1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months

Date de péremption: 12 months

Détails sur GSTa2

Antigène: GSTa2 (Glutathione S-Transferase alpha 2 (GSTa2))

Autre désignation: GSTA2

Sujet:

Synonyms: Glutathione S-transferase A2|GST HA subunit 2|GST class-alpha member 2|GST-gamma|GSTA2-2|GTH2|GSTA2|GST2

Background: Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. These enzymes function in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding these enzymes are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of some drugs. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-tranferase belonging to the alpha class. The alpha class genes, located in a cluster mapped to chromosome 6, are the most abundantly expressed glutathione S-transferases in liver. In addition to metabolizing bilirubin and certain anti- cancer drugs in the liver, the alpha class of these enzymes exhibit glutathione peroxidase activity thereby protecting the cells from reactive oxygen species and the products of peroxidation.

Poids moléculaire: 25 kDa

ID gène: 2939

UniProt: P09210