GADD45GIP1 anticorps

N° du produit ABIN7114772

L’anticorps anti-GADD45GIP1 Polyclonal Lapin est utilisé pour la détection de GADD45GIP1 dans des échantillons de Humain, Souris et Rat. Il a été validé pour ELISA, WB et IP.

Aperçu rapide pour GADD45GIP1 anticorps (ABIN7114772)

Antigène: GADD45GIP1 (Growth Arrest and DNA-Damage-Inducible, gamma Interacting Protein 1 (GADD45GIP1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GADD45GIP1 est non-conjugé

Application: ELISA, Western Blotting (WB), Immunoprecipitation (IP)

Détail du produit anti-GADD45GIP1 anticorps

Fonction: GADD45GIP1 antibody

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: growth arrest and DNA-damage-inducible, gamma interacting protein 1

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:2000, IP: 1:200-1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months

Date de péremption: 12 months

Détails sur GADD45GIP1

Antigène: GADD45GIP1 (Growth Arrest and DNA-Damage-Inducible, gamma Interacting Protein 1 (GADD45GIP1))

Autre désignation: GADD45GIP1

Sujet:

Synonyms: Large ribosomal subunit protein mL64|39S ribosomal protein L59, mitochondrial (MRP-L59)|CKII beta-associating protein|CR6-interacting factor 1 (CRIF1)|Growth arrest and DNA damage-inducible proteins-interacting protein 1|Papillomavirus L2-interacting nuclear protein 1 (PLINP, PLINP-1)|p53-responsive gene 6 protein|GADD45GIP1|MRPL59|PLINP1|PRG6

Background: Acts as a negative regulator of G1 to S cell cycle phase progression by inhibiting cyclin-dependent kinases. Inhibitory effects are additive with GADD45 proteins but occurs also in the absence of GADD45 proteins. Acts as a repressor of the orphan nuclear receptor NR4A1 by inhibiting AB domain-mediated transcriptional activity. May be involved in the hormone-mediated regulation of NR4A1 transcriptional activity. May play a role in mitochondrial protein synthesis.

Poids moléculaire: 25-28 kDa

ID gène: 90480

UniProt: Q8TAE8